Key Subheadings

Subheadings are Emtree terms that are used as concept modifiers and they provide information about the context of the specific drug or disease. We distinguish between disease subheadings and drug subheadings. Some subheadings are displayed as key subheadings, which are subheadings supplemented with additional information, showing drug-drug and drug-disease relationships

Drug key subheadings are:
 
·         Drug therapy: All diseases treated with the indexed drug in the current study are listed.
·         Adverse drug reaction: All adverse effects reported for the indexed drug in the current study are listed.
·         Drug comparison: All drugs compared to the indexed drug, within the same study, are listed.
·         Drug combination: All drugs given concomitantly with the indexed drug are listed.
·         Drug interaction: All drugs that show an interaction with the indexed drug are listed.
 
For the Drug Key Subheading Adverse drug reaction, the reported adverse effect(s) in the article are also indexed as diseases with the disease key subheading side effect, linked to the drug(s) causing the specific side effect(s). Not all Adverse drug reactions are Key Subheadings
 
Example:
 
cimetidine*adverse drug reaction*constipation
constipation*side effect*cimetidine
 
For the drug key subheading drug therapy, the reported (treated) disease(s) in the article are also indexed as diseases with the same disease key subheading drug therapy, linked to the drug(s) used to treat the diseases.
 
Example:
 
cimetidine*drug therapy*stomach ulcer
stomach ulcer*drug therapy*cimetidine
           
 
Disease key subheadings are:
 
·         Drug therapy: for this key subheading, all drugs are listed that are used in the study to treat the indexed disease.
·         Side effect: for this key subheading, all drugs are listed that, in the current study, are reported to cause the indexed side effect.
 
Key Subheadings are available in Embase from January 2007, apart from drug therapy, which is available from March 2009. Over 100,000 Embase-sourced records are enhanced each year, records sourced uniquely from Medline (and Embase conference items) will not have Key Subheadings.
Key subheadings are displayed in both Embase Search Results and Record View
Find out more about Subheadings and indexing in our Indexing Guide.